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Sertralinesold under the trade name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor SSRI class. Common side effects include diarrheasexual dysfunctionand troubles with sleep. Sertraline side effects of breast enhancers
approved for medical use in the United States in and initially sold by Pfizer. It is unclear if sertraline is any different than another SSRI paroxetine for depression. Evidence does not show a benefit in children with depression. With depression in dementia, there is no benefit compared to either placebo or mirtazapine. Tricyclic antidepressants TCAs as a group are considered to work better than SSRIs for melancholic depression  and in inpatients,  but not necessarily for simply more severe depression.